Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,000+ records

Systematic review / meta-analysis 2020
General medicine and research

Lactoferrin Concentration in Human Tears and Ocular Diseases: A Meta-Analysis.

Investigative ophthalmology & visual science

Purpose To evaluate the potential of lactoferrin (Lf) as a diagnostic biomarker for ocular diseases using a meta-analytic approach. Methods All original studies reporting an estimate of the average Lf concentration in healthy subjects and those affected by ocu

Systematic review / meta-analysis 2020
Cancer and oncology

MRI Assessment of Complete Response to Preoperative Chemoradiation Therapy for Rectal Cancer: 2020 Guide for Practice from the Korean Society of Abdominal Radiology.

Korean journal of radiology

Objective To provide an evidence-based guide for the MRI interpretation of complete tumor response after neoadjuvant chemoradiation therapy (CRT) for rectal cancer using visual assessment on T2-weighted imaging (T2) and diffusion-weighted imaging (DWI). Materi

Systematic review / meta-analysis 2018
Cancer and oncology

Platelet-to-lymphocyte ratio in the setting of liver transplantation for hepatocellular cancer: A systematic review and meta-analysis.

World journal of gastroenterology

Aim To perform a systematic review and meta-analysis on platelet-to-lymphocyte ratio (PLR) as a risk factor for post-transplant hepatocellular cancer (HCC) recurrence. Methods A systematic literature search was performed using PubMed. Participants of any age a

Systematic review / meta-analysis 2019
Lungs and breathing

Porcine vs bovine surfactant therapy for preterm neonates with RDS: systematic review with biological plausibility and pragmatic meta-analysis of respiratory outcomes.

Respiratory research

Background Bovine surfactants are known to be clinically equivalent but it is unclear if porcine or bovine surfactants at their licensed dose should be preferred to treat respiratory distress syndrome in preterm neonates. Methods We performed a comprehensive r

Systematic review / meta-analysis 2021
Prevention and public health

Probiotics for the Prevention of Antibiotic-associated Diarrhea in Adults: A Meta-Analysis of Randomized Placebo-Controlled Trials.

Journal of clinical gastroenterology

Objective This meta-analysis aims to combine the latest research evidence to assess the effect of probiotics on preventing antibiotic-associated diarrhea (AAD) in adults. Methods PubMed, Cochrane Library, EMBASE, and Web of Science were searched for randomized

Systematic review / meta-analysis 2021
Prevention and public health

Promoting physical activity in primary care: a systematic review and meta-analysis.

The British journal of general practice : the journal of the Royal College of General Practitioners

Background Promoting physical activity is an important part of patient care in primary care and has been investigated in many studies with a wide range of intervention characteristics, often including external support. It is unclear, however, if promoting phys

Systematic review / meta-analysis 2022
Mental health

Psychological and Social Impact of HIV on Women Living with HIV and Their Families in Low- and Middle-Income Asian Countries: A Systematic Search and Critical Review.

International journal of environmental research and public health

Human Immunodeficiency Virus (HIV) infection adds a significant burden to women in Low- and Middle-Income Countries (LMICs), often leading to severe detrimental impact, not only on themselves, but also on their families and communities. Given that more than ha

Systematic review / meta-analysis 2018
Heart and blood vessels

Quantitative myocardial perfusion evaluation with positron emission tomography and the risk of cardiovascular events in patients with coronary artery disease: a systematic review of prognostic studies.

European heart journal. Cardiovascular Imaging

Aims To evaluate the prognostic value of quantitative myocardial perfusion imaging with positron emission tomography (PET) for adverse cardiovascular outcomes in patients with known or suspected coronary artery disease (CAD). Methods and results A search in ME

Systematic review / meta-analysis 2021
Prevention and public health

Ratio of asymptomatic COVID-19 cases among ascertained SARS-CoV-2 infections in different regions and population groups in 2020: a systematic review and meta-analysis including 130 123 infections from 241 studies.

BMJ open

Introduction Asymptomatic infection of SARS-CoV-2 may lead to silent community transmission and compromise the COVID-19 pandemic control measures. We aimed to estimate the rate of asymptomatic COVID-19 from published studies and compare this rate among differe

Systematic review / meta-analysis 2020
Heart and blood vessels

Relationships Between Heart Rate Variability, Occupational Performance, and Fitness for Tactical Personnel: A Systematic Review.

Frontiers in public health

Objectives: Heart Rate Variability has gained substantial interest in both clinical and athletic settings as a measurement tool for quantifying autonomic nervous system activity and psychophysiological stress. However, its uses in tactical work settings, such

Systematic review / meta-analysis 2022
Infections and immunity

Risk of SARS-CoV-2 infection in migrants and ethnic minorities compared with the general population in the European WHO region during the first year of the pandemic: a systematic review.

BMC public health

Background Migrants and ethnic minorities have suffered a disproportionate impact of the COVID-19 pandemic compared to the general population from different perspectives. Our aim was to assess specifically their risk of infection in the 53 countries belonging

Systematic review / meta-analysis 2020
Infections and immunity

Seroprevalence of Crimean-Congo hemorrhagic fever in humans in the World Health Organization European region: A systematic review.

PLoS neglected tropical diseases

Background Crimean-Congo hemorrhagic fever (CCHF) is an emerging infectious disease caused by a Nairovirus. CCHF is a tick-borne disease that is predominantly associated with Hyalomma ticks and have a widespread distribution in Africa, Asia and Europe. CCHF us

Systematic review / meta-analysis 2019
Prevention and public health

Smartphone-Based Health Program for Improving Physical Activity and Tackling Obesity for Young Adults: A Systematic Review and Meta-Analysis.

International journal of environmental research and public health

The need for physical activity for health promotion is recognized, yet young adults still perform insufficient physical activity. Smartphone health programs can be applied easily without time and space constraints, and various mobile health programs based on s