Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,000+ records

Systematic review / meta-analysis 2020
Heart and blood vessels

Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Background Since being first reported in Wuhan, China, in December 8, 2019, the outbreak of the novel coronavirus, now known as COVID-19, has spread globally. Some case studies regarding the characteristics and outcome of patients with COVID-19 have been publi

Systematic review / meta-analysis 2020
Mental health

Prevalence of psychological morbidities among general population, healthcare workers and COVID-19 patients amidst the COVID-19 pandemic: A systematic review and meta-analysis.

Psychiatry research

This review was done to synthesize the existing evidence on the prevalence of various psychological morbidities among general public, healthcare workers and COVID-19 patients amidst this pandemic situation. Systematic searches were conducted in various databas

Systematic review / meta-analysis 2020
Diabetes and metabolism

Obesity in patients with COVID-19: a systematic review and meta-analysis.

Metabolism: clinical and experimental

Background Obesity is common in patients with coronavirus disease 2019 (COVID-19). The effects of obesity on clinical outcomes of COVID-19 warrant systematical investigation. Objective This study explores the effects of obesity with the risk of severe disease

Systematic review / meta-analysis 2020
Heart and blood vessels

Predictive symptoms and comorbidities for severe COVID-19 and intensive care unit admission: a systematic review and meta-analysis.

International journal of public health

Objectives COVID-19 has a varied clinical presentation. Elderly patients with comorbidities are more vulnerable to severe disease. This study identifies specific symptoms and comorbidities predicting severe COVID-19 and intensive care unit (ICU) admission. Met

Systematic review / meta-analysis 2021
Mental health

Prevalence of stress, depression, anxiety and sleep disturbance among nurses during the COVID-19 pandemic: A systematic review and meta-analysis.

Journal of psychosomatic research

Background The new coronavirus disease's (COVID-19) high risk of infection can increase the workload of healthcare workers, especially nurses, as they are most of the healthcare workforce. These problems can lead to psychological problems. Therefore, the aim o

Systematic review / meta-analysis 2021
Mental health

Global prevalence of mental health problems among healthcare workers during the Covid-19 pandemic: A systematic review and meta-analysis.

International journal of nursing studies

Background Healthcare workers are at high risk of developing mental health issues during the coronavirus disease 2019 (COVID-19) pandemic. However, there is a need for a full picture of mental health problems with comprehensive analysis among healthcare worker

Systematic review / meta-analysis 2020
Infections and immunity

Thrombosis risk associated with COVID-19 infection. A scoping review.

Thrombosis research

Background Infection by the 2019 novel coronavirus (COVID-19) has been reportedly associated with a high risk of thrombotic complications. So far information is scarce and rapidly emerging. Methods We conducted a scoping review using a single engine search for

Systematic review / meta-analysis 2021
Mental health

Prevalence of anxiety in the COVID-19 pandemic: An updated meta-analysis of community-based studies.

Progress in neuro-psychopharmacology & biological psychiatry

Background The unprecedented worldwide crisis caused by the rapid spread of COVID-19 and the restrictive public health measures enforced by some countries to slow down its transmission have severely threatened the physical and mental wellbeing of communities g

Systematic review / meta-analysis 2020
Diabetes and metabolism

Diabetes as a risk factor for greater COVID-19 severity and in-hospital death: A meta-analysis of observational studies.

Nutrition, metabolism, and cardiovascular diseases : NMCD

Aims To estimate the prevalence of established diabetes and its association with the clinical severity and in-hospital mortality associated with COVID-19. Data synthesis We systematically searched PubMed, Scopus and Web of Science, from 1st January 2020 to 15t

Randomised controlled trial 2018
Digestive system

Diagnostic accuracy of magnetic resonance enterography and small bowel ultrasound for the extent and activity of newly diagnosed and relapsed Crohn's disease (METRIC): a multicentre trial.

The lancet. Gastroenterology & hepatology

Background Magnetic resonance enterography (MRE) and ultrasound are used to image Crohn's disease, but their comparative accuracy for assessing disease extent and activity is not known with certainty. Therefore, we did a multicentre trial to address this issue

Systematic review / meta-analysis 2021
Mental health

The prevalence of anxiety and depression among healthcare workers during the COVID-19 pandemic: An umbrella review of meta-analyses.

Progress in neuro-psychopharmacology & biological psychiatry

Background Healthcare workers, who are at the forefront of the fight against COVID-19, are particularly susceptible to physical and mental health consequences such as anxiety and depression. The aim of this umbrella review of meta-analyses is to determine the

Randomised controlled trial 2022
Heart and blood vessels

Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial.

The Lancet. Haematology

Background Time to treatment matters in traumatic haemorrhage but the optimal prehospital use of blood in major trauma remains uncertain. We investigated whether use of packed red blood cells (PRBC) and lyophilised plasma (LyoPlas) was superior to use of 0·9%

Systematic review / meta-analysis 2022
Infections and immunity

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Background Available data show that COVID-19 vaccines may be less effective in immunocompromised populations, who are at increased risk of severe COVID-19. Objectives We conducted a systematic review of literature to assess immunogenicity, efficacy and effecti

Systematic review / meta-analysis 2021
Mental health

Government response moderates the mental health impact of COVID-19: A systematic review and meta-analysis of depression outcomes across countries.

Journal of affective disorders

Background The COVID-19 pandemic represents a public health, economic and mental health crisis. We hypothesized that timely government implementation of stringent measures to reduce viral transmission would benefit mental health, as evidenced by reduced rates

Systematic review / meta-analysis 2021
Diabetes and metabolism

Diabetes is most important cause for mortality in COVID-19 hospitalized patients: Systematic review and meta-analysis.

Reviews in endocrine & metabolic disorders

The presence of SARS-CoV-2 was officially documented in Europe at the end of February 2020. Despite many observations, the real impact of COVID-19 in the European Union (EU), its underlying factors and their contribution to mortality and morbidity outcomes wer

Systematic review / meta-analysis 2020
Infections and immunity

Telehealth in Urology: A Systematic Review of the Literature. How Much Can Telemedicine Be Useful During and After the COVID-19 Pandemic?

European urology

Context Coronavirus disease 2019 (COVID-19) pandemic has caused increased interest in the application of telehealth to provide care without exposing patients and physicians to the risk of contagion. The urological literature on the topic is sparse. Objective T