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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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4,000+ records

Systematic review / meta-analysis 2018
Digestive system

What maximizes the effectiveness and implementation of technology-based interventions to support healthcare professional practice? A systematic literature review.

BMC medical informatics and decision making

Background Technological support may be crucial in optimizing healthcare professional practice and improving patient outcomes. A focus on electronic health records has left other technological supports relatively neglected. Additionally, there has been no comp

Systematic review / meta-analysis 2018
Digestive system

A pooled analysis of mesenchymal stem cell-based therapy for liver disease.

Stem cell research & therapy

Background Liver disease is a major cause of death and disability. Mesenchymal stem cells (MSCs) show promise for the treatment of liver disease. However, whether MSC-based therapy is more effective than conventional treatment is unclear, as are the optimal MS

Systematic review / meta-analysis 2018
Heart and blood vessels

Albuminuria, serum creatinine, and estimated glomerular filtration rate as predictors of cardio-renal outcomes in patients with type 2 diabetes mellitus and kidney disease: a systematic literature review.

BMC nephrology

Background Albuminuria, elevated serum creatinine and low estimated glomerular filtration rate (eGFR) are pivotal indicators of kidney decline. Yet, it is uncertain if these and emerging biomarkers such as uric acid represent independent predictors of kidney d

Systematic review / meta-analysis 2019
Brain and nervous system

Astragaloside IV Supplementation Promotes A Neuroprotective Effect in Experimental Models of Neurological Disorders: A Systematic Review.

Current neuropharmacology

Background Neurological disorders constitute a growing worldwide concern due to the progressive aging of the population and the risky behavior they represent. Herbal medicines have scientific relevance in the treatment of these pathologies. One of these substa

Systematic review / meta-analysis 2022
Women's health

Bioengineering trends in female reproduction: a systematic review.

Human reproduction update

Background To provide the optimal milieu for implantation and fetal development, the female reproductive system must orchestrate uterine dynamics with the appropriate hormones produced by the ovaries. Mature oocytes may be fertilized in the fallopian tubes, an

Systematic review / meta-analysis 2020
Prevention and public health

Breast Cancer Primary Prevention and Diet: An Umbrella Review.

International journal of environmental research and public health

Introduction: Many studies have been published, but none have pooled the useful evidence available in the literature to produce guidelines and health policies promoting healthy eating styles to prevent breast cancer (BC). The present study aimed to summarize t

Systematic review / meta-analysis 2020
Mental health

Burnout in Palliative Care Nurses, Prevalence and Risk Factors: A Systematic Review with Meta-Analysis.

International journal of environmental research and public health

Palliative care nurses are exposed to hard situations, death, and duel feelings in their daily practice. These, and other work stressors, can favor burnout development. Thus, it is important to analyze the prevalence and risk factors of burnout in palliative c

Systematic review / meta-analysis 2021
General medicine and research

Doctors and Nurses: A Systematic Review of the Risk and Protective Factors in Workplace Violence and Burnout.

International journal of environmental research and public health

The present study aims analyze the risk factors that lead to high levels of burnout among nurses and physicians and the protective factors that prevent them. Thus, it is also intended to explore the possible correlation between physical and verbal violence pro

Systematic review / meta-analysis 2022
Diabetes and metabolism

Effect of aerobic exercise on waist circumference in adults with overweight or obesity: A systematic review and meta-analysis.

Obesity reviews : an official journal of the International Association for the Study of Obesity

Excess visceral adiposity contributes to elevated cardiometabolic risk, and waist circumference is commonly used as a surrogate measure of visceral adipose tissue. Although regular aerobic exercise is known to improve abdominal obesity, its effect on waist cir

Systematic review / meta-analysis 2022
Prevention and public health

Efficacy of Exercise on Muscle Function and Physical Performance in Older Adults with Sarcopenia: An Updated Systematic Review and Meta-Analysis.

International journal of environmental research and public health

This study aimed to analyze the efficacy of exercise interventions on muscle strength, muscle mass, and physical performance in older adults with sarcopenia. Randomized controlled studies assessing exercise effects on sarcopenia were searched in Web of Science

Systematic review / meta-analysis 2021
Lungs and breathing

Estimation of the Prevalence of Progressive Fibrosing Interstitial Lung Diseases: Systematic Literature Review and Data from a Physician Survey.

Advances in therapy

Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. H

Systematic review / meta-analysis 2020
Infections and immunity

Genetic variants of the human host influencing the coronavirus-associated phenotypes (SARS, MERS and COVID-19): rapid systematic review and field synopsis.

Human genomics

The COVID-19 pandemic has strengthened the interest in the biological mechanisms underlying the complex interplay between infectious agents and the human host. The spectrum of phenotypes associated with the SARS-CoV-2 infection, ranging from the absence of sym

Systematic review / meta-analysis 2020
General medicine and research

Health Literacy in Surgery.

Health literacy research and practice

Background Low health literacy is associated with poor health outcomes in many chronic diseases and may have an important role in determining surgical outcomes. This study aims to comprehensively review the current state of science on adult health literacy in

Systematic review / meta-analysis 2019
General medicine and research

Intralesional Injection of Botulinum Toxin Type A Compared with Intralesional Injection of Corticosteroid for the Treatment of Hypertrophic Scar and Keloid: A Systematic Review and Meta-Analysis.

Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND The optimal treatment for hypertrophic scar and keloid remains controversial. Therefore, the aim of this systematic review and meta-analysis was to compare the effectiveness of intralesional injection of botulinum toxin type A compared with placebo

Systematic review / meta-analysis 2022
Heart and blood vessels

Machine learning methods for functional recovery prediction and prognosis in post-stroke rehabilitation: a systematic review.

Journal of neuroengineering and rehabilitation

Background Rehabilitation medicine is facing a new development phase thanks to a recent wave of rigorous clinical trials aimed at improving the scientific evidence of protocols. This phenomenon, combined with new trends in personalised medical therapies, is ex

Systematic review / meta-analysis 2018
Infections and immunity

Mosquito repellents for malaria prevention.

The Cochrane database of systematic reviews

Background Malaria is an important cause of illness and death across endemic regions. Considerable success against malaria has been achieved within the past decade mainly through long-lasting insecticide-treated nets (LLINs). However, elimination of the diseas

Systematic review / meta-analysis 2018
Heart and blood vessels

Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.

Arthritis research & therapy

Background Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hypertension and diuretic use. Methods We conduc