Povezanost alergijskog rinitisa s opstruktivnom apnejom u snu: meta-analiza.
Medicine
Sažetak istraživanja
Istorijat Koegzistencija alergijskog rinitisa (AR) i opstruktivne apneje u snu (OSA) je uobičajena pojava u kliničkoj praksi. AR se dugo smatrao faktorom rizika za OSA. Međutim, odnos nije potpuno jasan. Stoga smo sproveli meta-analizu kako bismo procijenili prevalenciju AR kod poremećaja disanja u snu (SDB)/OSA i njihov odnos.
Metode Sveobuhvatna pretraga literature obavljena je u PubMed/Medline, Google Scholar, Wiley Online Library, EMBASE i Web of Science. Podaci su analizirani i objedinjeni kako bi se procijenila veličina efekta (ES)/odnos šanse (OR) sa 95% intervalima povjerenja (95%CI). Heterogenost je kvantificirana i procijenjena Q-testom na bazi hi-kvadrata i I2 testom, pri čemu je P 50% ukazivao na dokaz heterogenosti.
Rezultati 44 studije koje su sadržavale 6086 učesnika uključene su u ovu meta-analizu. Za odrasle, prevalencija AR je bila 22,8 (95% CI, 15,0-30,6) % u SDB i 35,2 (95% CI, 25,6-44,7) % u OSA. Kod djece sa SDB i OSA, prevalencija AR je bila 40,8 (95% CI, 24,3-57,2) %, odnosno 45,2 (95% CI, 25,4-65,0) %. The odds ratios of prevalence of the SDB pediatric patients with AR was 2.12 (95%CI, 1.75, 2.57; P
Conclusion The prevalence of AR in OSA/SDB is considerably high and children with SDB suffering from a higher incidence of AR than non-SDB. OSA adults accompanied with AR do not have any influences on sleep parameters.
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Association of allergic rhinitis with obstructive sleep apnea: A meta-analysis.
Background The co-existence of allergic rhinitis (AR) and obstructive sleep apnea (OSA) is a common phenomenon in clinical practice. AR has long been considered a risk factor for OSA. However, the relationship is not completely clear. Therefore, we conducted a meta-analysis to evaluate the prevalence of AR in sleep-disordered breathing (SDB) /OSA and their relationship.
Methods A comprehensive literature search was performed in PubMed/Medline, Google Scholar, Wiley Online Library, EMBASE, and Web of Science. Data were analyzed and pooled to estimate effect size (ES) /odds ratio (OR) with 95% confidence intervals (95%CI). Heterogeneity was quantified and evaluated by chi-squared-based Q-test and I2 test, with P 50% indicating evidence of heterogeneity.
Results 44 studies contained 6086 participants were included in this meta-analysis. For adults, the prevalence of AR was 22.8 (95% CI, 15.0-30.6) % in SDB and 35.2 (95% CI, 25.6-44.7) % in OSA. In children with SDB and OSA, the prevalence of AR was 40.8 (95% CI, 24.3-57.2) %, and 45.2 (95% CI, 25.4-65.0) % respectively. The odds ratios of prevalence of the SDB pediatric patients with AR was 2.12 (95%CI, 1.75, 2.57; P
Conclusion The prevalence of AR in OSA/SDB is considerably high and children with SDB suffering from a higher incidence of AR than non-SDB. OSA adults accompanied with AR do not have any influences on sleep parameters.
Izvorni podaci
- DOI
- 10.1097/md.0000000000013783
- PMID
- 30572534
- PMCID
- PMC6319794
- Provjereno
- 2026-07-26
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