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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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4,000+ records

Systematic review / meta-analysis 2019
Lungs and breathing

Comparison of mortality and complications between bilateral simultaneous and staged total hip arthroplasty: A systematic review and meta-analysis.

Medicine

Background Total hip arthroplasty (THA) relieves pain and restores function in patients with severe rheumatoid arthritis and osteoarthritis. Over the past few decades, several authors have attempted to assess the efficacy and safety of simultaneous bilateral T

Systematic review / meta-analysis 2022
Prevention and public health

Cost-effectiveness of interventions for the prevention and control of COVID-19: Systematic review of 85 modelling studies.

Journal of global health

Background We aimed to quantitatively summarise the health economic evaluation evidence of prevention and control programs addressing COVID-19 globally. Methods We did a systematic review and meta-analysis to assess the economic and health benefit of intervent

Systematic review / meta-analysis 2021
Heart and blood vessels

Dexmedetomidine reduces the incidence of postoperative delirium after cardiac surgery: a meta-analysis of randomized controlled trials.

BMC anesthesiology

Background The role of dexmedetomidine in preventing postoperative delirium (POD) after cardiac surgery remains controversial because of several recent trials with negative results. We aimed to perform an updated meta-analysis of randomized controlled trials (

Systematic review / meta-analysis 2022
Infections and immunity

Does metformin affect outcomes in COVID-19 patients with new or pre-existing diabetes mellitus? A systematic review and meta-analysis.

British journal of clinical pharmacology

Aims The COVID-19 pandemic is a global public health emergency and patients with diabetes mellitus (DM) are disproportionately affected, exhibiting more severe outcomes. Recent studies have shown that metformin is associated with improved outcomes in patients

Systematic review / meta-analysis 2019
General medicine and research

Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages: individual participant meta-analysis of five cohorts.

Scientific reports

Evidence on the association between functioning of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages is mixed. We undertook a systematic review (until October 2016) and individual participant data (IPD) meta-analysis to test

Systematic review / meta-analysis 2019
General medicine and research

Economic evaluation of clinical quality registries: a systematic review.

BMJ open

Objectives The objective of this systematic review was to examine the existing evidence base for the cost-effectiveness or cost-benefit of clinical quality registries (CQRs). Design Systematic review and narrative synthesis. Data sources Nine electronic biblio

Systematic review / meta-analysis 2021
Children's health

Education Technology in Orthodontics and Paediatric Dentistry during the COVID-19 Pandemic: A Systematic Review.

International journal of environmental research and public health

Over the last decade, medical education changed from traditional teaching methods to telematic and networking scholar and e-learning approach. The objective of the present systematic review was to evaluate the effectiveness and teachers/student's acceptability

Systematic review / meta-analysis 2018
Heart and blood vessels

Effect of intracoronary agents on the no-reflow phenomenon during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction: a network meta-analysis.

BMC cardiovascular disorders

Background Despite the restoration of epicardial flow after primary percutaneous coronary intervention (PPCI), myocardial reperfusion remains impaired in a significant proportion of patients. We performed a network meta-analysis to assess the effect of 7 intra

Systematic review / meta-analysis 2021
Heart and blood vessels

Effectiveness of Mechanical Chest Compression Devices over Manual Cardiopulmonary Resuscitation: A Systematic Review with Meta-analysis and Trial Sequential Analysis.

The western journal of emergency medicine

Introduction Our goal was to systematically review contemporary literature comparing the relative effectiveness of two mechanical compression devices (LUCAS and AutoPulse) to manual compression for achieving return of spontaneous circulation (ROSC) in patients

Systematic review / meta-analysis 2020
Heart and blood vessels

Effectiveness of Mobile Phone-Based Interventions for Improving Health Outcomes in Patients with Chronic Heart Failure: A Systematic Review and Meta-Analysis.

International journal of environmental research and public health

Mobile phone-based interventions are increasingly used to prevent adverse health outcomes in heart failure patients. However, the effects of mobile phone-based interventions on the health outcomes of heart failure patients remain unclear. Our review aims to sy

Systematic review / meta-analysis 2022
Diabetes and metabolism

Effects of vitamin D treatment on thyroid function and autoimmunity markers in patients with Hashimoto's thyroiditis-A meta-analysis of randomized controlled trials.

Journal of clinical pharmacy and therapeutics

Introduction Recent evidence suggested that vitamin D deficiency was associated with Hashimoto's thyroiditis (HT) pathogenesis and thyroid hypofunction. This study aimed to investigate whether vitamin D supplementation would be effective in the prevention and

Systematic review / meta-analysis 2019
Prevention and public health

Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research.

BMC geriatrics

Background Nursing home residents (NHR) are characterized by increasing frailty, multimorbidity and care dependency. These conditions result in frequent hospital transfers which can lead to negative effects on residents' health status and are often avoidable.

Systematic review / meta-analysis 2022
Brain and nervous system

Gait Impairment in Traumatic Brain Injury: A Systematic Review.

Sensors (Basel, Switzerland)

Introduction Gait impairment occurs across the spectrum of traumatic brain injury (TBI); from mild (mTBI) to moderate (modTBI), to severe (sevTBI). Recent evidence suggests that objective gait assessment may be a surrogate marker for neurological impairment su

Systematic review / meta-analysis 2020
Bones, joints and rehabilitation

Higher risk of revision in total knee arthroplasty after high tibial osteotomy: a systematic review and updated meta-analysis.

BMC musculoskeletal disorders

Background High tibial osteotomy is commonly performed in young patients with high activity demand. Several studies have reported outcome of HTO. The reported 10-year survival ranged from 79 to 97.6%. The reported 15-year survival ranged from 56 to 65.5%, resu

Systematic review / meta-analysis 2020
Mental health

Human zoonotic tuberculosis and livestock exposure in low- and middle-income countries: A systematic review identifying challenges in laboratory diagnosis.

Zoonoses and public health

Background Zoonotic tuberculosis (zTB) accounts for 1.4% of the global tuberculosis burden, with the largest disease burden in low- and middle-income countries (LMICs). These populations have increased exposure to zTB due to livestock rearing practices and raw

Systematic review / meta-analysis 2020
Children's health

Immunization coverage and its determinant factors among children aged 12-23 months in Ethiopia: a systematic review, and Meta- analysis of cross-sectional studies.

BMC pediatrics

Background Immunization is the process by which a person is made immune or resistant to an infectious disease, typically by the administration of vaccine. Vaccination coverage for other single vaccines ranged from 49.1% for PCV to 69.2% for BCG vaccine. The va